Second law of worker entropy
The background level of resentment, misunderstanding and discomfort which is an inevitable by-product of modern corporate discourse. It will eventually lead to the boredom heat death of the universe.
Different types of activity generate more or less of this kind of entropy. Conference calls — especially all-hands conference calls — generate dangerously high levels.
Can be cured with alcohol, but there is a curious paradox, as overdoing the sauce (which, on a conference call, can be tremendously tempting) can itself lead to total collapse through the inebriation event horizon into a black hole of soul-crushing despair.
So it’s either crushing your soul into an infinitesimal point of space-time, or regressing to a sunless, tepid expanse, having infinite extension in every direction except the one you want to go in, of maximum possible ennui.